A Further Case of Diaphysial Aclasis, (Multiple Exostosis) with a Marked Family History

Seven Cases of Diaphysial Aclasis (Multiple Exostosis) in Indians, Including Four Cases from One Family

Periodic hypersomnia, congenital ectodermal disorders and multiple exostosis.

A case of periodic hypersomnia in an 11-year-old female with the unique features of mental deficiency, incontinentia pigmenti, acanthosis nigricans and hereditary multiple exostosis (diaphysial aclasis) is reported. The clinical, polysomnographic and Multiple Sleep Latency test features of this case with a follow up of seven years are consistent with a diagnosis of periodic (intermittent) exces...

A Case of Diaphysial Aclasis

By P. N. RAY, b.a., m.b., f.r.c.s. (Eng.) (Surgeon, Ccirmichael Medical College Hospitals, and Additional Surgeon, General Hospital, Howrah) This rare condition is known under a multiplicity of names, e.g., multiple cartilaginous exostoses, hereditary multiple exostoses, etc. The patient, a Hindu male child aged 12, complained of swelling around both the knees and the left ankle with hard nodul...

Bone Growth in Diaphyslal

An example of cartilaginous exostoses-believed by some to be the first described in detail in the literature-was reported in the Guy’s Hospital Reports of the Lancet of July 23, 1 825. However, it is certain that the condition was known at least half a century before that. In the series of Lectures on the Principles of Surgery which John Hunter delivered in I 786 and 1 787 he described the cond...

Hereditary multiple exostoses.

Hereditary multiple exostoses (HME) is a skeletal disorder which primarily affects enchondral bone during growth. It is characterised by multiple exostoses, usually arising in the juxtaepiphyseal region of the long bones. Exostoses that affect "almost every bone in the body" were first mentioned by John Hunter in his Lectures on the principles of surgery in 1786.1 The first family affected by H...